shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(OR5B3-shRNA-Seq5)(CAT#: AdV-SI2122WQ)

This product is a OR5B3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR5B3 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR5B3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR5B3-shRNA-Seq5
Related Target/Protein OR5B3
Region CDS
TargetSeq CCTGGGAATTATTGTATTGAT
NCBI RefSeq NM_001005469
Alternative Names OR5B13; OST129; OR11-239
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 441608
Uniprot ID Q8NH48

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