shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Tcte1-shRNA-Seq3)(CAT#: AdV-SI1899WQ)
This product is a Tcte1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Tcte1 gene may play a role in the assembly of N-DRC and be required for sperm motility. The expression of Tcte1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Tcte1-shRNA-Seq3 |
| Related Target/Protein | Tcte1 |
| Region | 3UTR |
| TargetSeq | GCTGACTAATTCAAACTCTTA |
| NCBI RefSeq | NM_013688 |
| Alternative Names | DRC5; D6S46; FAP155 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Infertility |
