shRNA Lentivirus (self-inactivating), p7SK-(Psme4-shRNA-Seq3)(CAT#: LV-SI3423WQ)

This product is a Psme4-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Psme4 gene is associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. The expression of Psme4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.