shRNA Lentivirus (self-inactivating), pH1-(LAMP3-shRNA-Seq1)(CAT#: LV-SI0740WQ)

This product is a LAMP3-shRNA encoding Lentivirus, which is based on HIV-1 serotype. LAMP3 regulates hepatic lipid metabolism through activating PI3K/Akt pathway. LAMP3 promotes the invasion of osteosarcoma cells via SPP1 signaling. LAMP3 expression correlated with poor clinical outcome in human ovarian cancer. The expression of LAMP3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.