shRNA Adeno-associated Virus Serotype 2, pU6-(Dos-shRNA-Seq1)(CAT#: AAV-SI2294WQ)
This product is a Dos-shRNA encoding AAV, which is based on AAV-2 serotype. The protein encoded by Dos gene negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. The expression of Dos-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | Dos-shRNA-Seq1 |
| Related Target/Protein | Dos |
| Region | CDS |
| TargetSeq | GCCGACTTCATTCAGTACATT |
| NCBI RefSeq | NM_015761 |
| Alternative Names | DOS; BARP; C19orf26; CBARP |
| Titer | >1*10^10 GC/mL |
