siRNA, Anti-C9orf78, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76104WQ-2OMe)

The product SIRGT76104WQ-2OMe is a type of small interfering RNA (siRNA) that targets C9orf78 gene and regulates the expression of gene. The siRNA interferes with the expression of C9orf78 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016520.2
Alternative Names HCA59; HSPC220; bA409K20.3
Related Diseases Emery-Dreifuss Muscular Dystrophy 4
Purification HPLC
Target Gene
Gene ID 51759
Uniprot ID Q9NZ63
Sub Cat Target Species Modification Scale  
SIRGT77104WQ-2F C9orf78 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78104WQ-2MOE C9orf78 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79104WQ-LNA C9orf78 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76104WQ-RB C9orf78 Human Ribo-modified Inquiry
SIRGT77104WQ-BB C9orf78 Human Backbone-modified Inquiry

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