siRNA, Anti-NKX3-1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT16055WQ-2OMe)
The product SIRGT16055WQ-2OMe is a type of small interfering RNA (siRNA) that targets NKX3-1 gene and regulates the expression of gene. The siRNA interferes with the expression of NKX3-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001256339.1; NM_006167.3 |
| Alternative Names | BAPX2; NKX3; NKX3.1; NKX3A |
| Related Diseases | Chromosome 8P Deletion, Prostatitis |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT17055WQ-2F | NKX3-1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT18055WQ-2MOE | NKX3-1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT19055WQ-LNA | NKX3-1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT16055WQ-RB | NKX3-1 | Human | Ribo-modified | ||
| SIRGT17055WQ-BB | NKX3-1 | Human | Backbone-modified |
