siRNA, Anti-TBX6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21542WQ-2OMe)

The product SIRGT21542WQ-2OMe is a type of small interfering RNA (siRNA) that targets TBX6 gene and regulates the expression of gene. The siRNA interferes with the expression of TBX6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004608.3
Alternative Names SCDO5
Related Diseases Spondylocostal Dysostosis
Purification HPLC
Target Gene
Gene ID 6911
Uniprot ID O95947
Sub Cat Target Species Modification Scale  
SIRGT22542WQ-2F TBX6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23542WQ-2MOE TBX6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24542WQ-LNA TBX6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21542WQ-RB TBX6 Human Ribo-modified Inquiry
SIRGT22542WQ-BB TBX6 Human Backbone-modified Inquiry

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