shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(SESN3-shRNA-Seq1)(CAT#: AdV-SI1713WQ)
This product is a SESN3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The SESN3 gene encodes a member of the sestrin family of stress-induced proteins and plays a role in lipid storage in obesity. The expression of SESN3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | SESN3-shRNA-Seq1 |
| Related Target/Protein | SESN3 |
| Region | CDS |
| TargetSeq | CGTACTAACTTTCTTGTGGAA |
| NCBI RefSeq | NM_144665 |
| Alternative Names | SEST3 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Obesity |
