shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Zpbp-shRNA-Seq4)(CAT#: AdV-SI1959WQ)
This product is a Zpbp-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida. The expression of Zpbp-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Zpbp-shRNA-Seq4 |
| Related Target/Protein | Zpbp |
| Region | CDS |
| TargetSeq | CCTGTGAAATATCCTTGATTA |
| NCBI RefSeq | NM_015785 |
| Alternative Names | ZPBP1 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Infertility |
