Recombinant adenovirus, pU6-(Human BACE1( K275R)), Overexpression(CAT#: AdV-GTOH0010WQ)

The product is an adenovirus vector containing the insertion of BACE1( K275R) gene. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Tropism Both nondividing and dividing cells
Insert BACE1( K275R)
Related Target/Protein Human BACE1
NCBI RefSeq NM_012104.4
Alternative Names ASP2, BACE, HSPC104
Titer >1.00E+10 PFU/mL
Related Diseases Alzheimer's disease
Application Overexpression
Target Gene
Gene ID 23621
Uniprot ID P56817

Related Products