shRNA Adeno-associated Virus Serotype 2, pU6-(Armc5-shRNA-Seq1)(CAT#: AAV-SI2334WQ)

This product is a Armc5-shRNA encoding AAV, which is based on AAV-2 serotype. The Armc5 gene encodes a member of the ARM (armadillo/beta-catenin-like repeat) superfamily. Mutations in this gene are associated with primary bilateral macronodular adrenal hyperplasia, which is also known as ACTH-independent macronodular adrenal hyperplasia 2. The expression of Armc5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.