shRNA Adeno-associated Virus Serotype 2, pU6-(SERINC5-shRNA-Seq1)(CAT#: AAV-SI0496WQ)

This product is a SERINC5-shRNA encoding AAV, which is based on AAV-2 serotype. The SERINC5 gene impairs the penetration of the viral particle into the cytoplasm and enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes. The expression of SERINC5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.