siRNA, Anti-ADA2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76016WQ-2OMe)

The product SIRGT76016WQ-2OMe is a type of small interfering RNA (siRNA) that targets ADA2 gene and regulates the expression of gene. The siRNA interferes with the expression of ADA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_177405.2
Alternative Names ADGF; CECR1; IDGFL; PAN; SNEDS
Related Diseases Sneddon Syndrome
Purification HPLC
Target Gene
Gene ID 51816
Uniprot ID Q9NZK5
Sub Cat Target Species Modification Scale  
SIRGT77016WQ-2F ADA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78016WQ-2MOE ADA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79016WQ-LNA ADA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76016WQ-RB ADA2 Human Ribo-modified Inquiry
SIRGT77016WQ-BB ADA2 Human Backbone-modified Inquiry

Related Products