siRNA, Anti-AKR1B15, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66603WQ-2OMe)

The product SIRGT66603WQ-2OMe is a type of small interfering RNA (siRNA) that targets AKR1B15 gene and regulates the expression of gene. The siRNA interferes with the expression of AKR1B15 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001080538.2
Alternative Names AKR1B10L; AKR1B10L; AK1R1B7; AKR1R1B7
Purification HPLC
Target Gene
Gene ID 441282
Uniprot ID C9JRZ8
Sub Cat Target Species Modification Scale  
SIRGT67603WQ-2F AKR1B15 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68603WQ-2MOE AKR1B15 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69603WQ-LNA AKR1B15 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66603WQ-RB AKR1B15 Human Ribo-modified Inquiry
SIRGT67603WQ-BB AKR1B15 Human Backbone-modified Inquiry

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