siRNA, Anti-ANGPT4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76036WQ-2OMe)

The product SIRGT76036WQ-2OMe is a type of small interfering RNA (siRNA) that targets ANGPT4 gene and regulates the expression of gene. The siRNA interferes with the expression of ANGPT4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015985.3
Alternative Names ANG3; ANG4
Related Diseases Gastrointestinal Stromal Tumor
Purification HPLC
Target Gene
Gene ID 51378
Uniprot ID Q9Y264
Sub Cat Target Species Modification Scale  
SIRGT77036WQ-2F ANGPT4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78036WQ-2MOE ANGPT4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79036WQ-LNA ANGPT4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76036WQ-RB ANGPT4 Human Ribo-modified Inquiry
SIRGT77036WQ-BB ANGPT4 Human Backbone-modified Inquiry

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