siRNA, Anti-ARHGAP11B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51290WQ-2OMe)

The product SIRGT51290WQ-2OMe is a type of small interfering RNA (siRNA) that targets ARHGAP11B gene and regulates the expression of gene. The siRNA interferes with the expression of ARHGAP11B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001039841.2
Alternative Names B'-T; FAM7B1
Related Diseases Chromosome 15Q13.3 Deletion Syndrome
Purification HPLC
Target Gene
Gene ID 89839
Uniprot ID Q3KRB8
Sub Cat Target Species Modification Scale  
SIRGT52290WQ-2F ARHGAP11B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53290WQ-2MOE ARHGAP11B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54290WQ-LNA ARHGAP11B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51290WQ-RB ARHGAP11B Human Ribo-modified Inquiry
SIRGT52290WQ-BB ARHGAP11B Human Backbone-modified Inquiry

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