siRNA, Anti-ASCL4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51885WQ-2OMe)

The product SIRGT51885WQ-2OMe is a type of small interfering RNA (siRNA) that targets ASCL4 gene and regulates the expression of gene. The siRNA interferes with the expression of ASCL4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_203436.2
Alternative Names HASH4; bHLHa44
Related Diseases Secondary Hypertrophic Osteoarthropathy
Purification HPLC
Target Gene
Gene ID 121549
Uniprot ID Q6XD76
Sub Cat Target Species Modification Scale  
SIRGT52885WQ-2F ASCL4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53885WQ-2MOE ASCL4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54885WQ-LNA ASCL4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51885WQ-RB ASCL4 Human Ribo-modified Inquiry
SIRGT52885WQ-BB ASCL4 Human Backbone-modified Inquiry

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