siRNA, Anti-C12orf29, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51449WQ-2OMe)

The product SIRGT51449WQ-2OMe is a type of small interfering RNA (siRNA) that targets C12orf29 gene and regulates the expression of gene. The siRNA interferes with the expression of C12orf29 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001009894.2
Related Diseases Senior-Loken Syndrome 6
Purification HPLC
Target Gene
Gene ID 91298
Uniprot ID Q8N999
Sub Cat Target Species Modification Scale  
SIRGT52449WQ-2F C12orf29 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53449WQ-2MOE C12orf29 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54449WQ-LNA C12orf29 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51449WQ-RB C12orf29 Human Ribo-modified Inquiry
SIRGT52449WQ-BB C12orf29 Human Backbone-modified Inquiry

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