siRNA, Anti-C9orf3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51122WQ-2OMe)

The product SIRGT51122WQ-2OMe is a type of small interfering RNA (siRNA) that targets C9orf3 gene and regulates the expression of gene. The siRNA interferes with the expression of C9orf3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001193329.1
Alternative Names AOPEP; AP-O; APO; C90RF3; ONPEP
Related Diseases Fanconi Anemia
Purification HPLC
Target Gene
Gene ID 84909
Uniprot ID Q8N6M6
Sub Cat Target Species Modification Scale  
SIRGT52122WQ-2F C9orf3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53122WQ-2MOE C9orf3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54122WQ-LNA C9orf3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51122WQ-RB C9orf3 Human Ribo-modified Inquiry
SIRGT52122WQ-BB C9orf3 Human Backbone-modified Inquiry

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