siRNA, Anti-C9orf72, 2'-MOE-modified(CAT#: SIRGT63283WQ-2MOE)
The product SIRGT63283WQ-2MOE is a type of small interfering RNA (siRNA) that targets C9orf72 gene and regulates the expression of gene. The siRNA interferes with the expression of C9orf72 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2'-O-methoxyethyl (2'-MOE) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001256054.2 |
| Alternative Names | ALSFTD; DENNL72; FTDALS; FTDALS1 |
| Related Diseases | Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1 |
| Purification | HPLC |