siRNA, Anti-CARMIL3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51400WQ-2OMe)

The product SIRGT51400WQ-2OMe is a type of small interfering RNA (siRNA) that targets CARMIL3 gene and regulates the expression of gene. The siRNA interferes with the expression of CARMIL3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_138360.3
Alternative Names C14orf121; LRRC16B; crml-1
Related Diseases Mucopolysaccharidosis, Type Ivb
Purification HPLC
Target Gene
Gene ID 90668
Uniprot ID Q8ND23
Sub Cat Target Species Modification Scale  
SIRGT52400WQ-2F CARMIL3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53400WQ-2MOE CARMIL3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54400WQ-LNA CARMIL3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51400WQ-RB CARMIL3 Human Ribo-modified Inquiry
SIRGT52400WQ-BB CARMIL3 Human Backbone-modified Inquiry

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