siRNA, Anti-CASC4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT61699WQ-2OMe)

The product SIRGT61699WQ-2OMe is a type of small interfering RNA (siRNA) that targets CASC4 gene and regulates the expression of gene. The siRNA interferes with the expression of CASC4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_138423.3
Alternative Names H63
Related Diseases Schizophrenia 5
Purification HPLC
Target Gene
Gene ID 113201
Uniprot ID Q6P4E1
Sub Cat Target Species Modification Scale  
SIRGT62699WQ-2F CASC4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT63699WQ-2MOE CASC4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT64699WQ-LNA CASC4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT61699WQ-RB CASC4 Human Ribo-modified Inquiry
SIRGT62699WQ-BB CASC4 Human Backbone-modified Inquiry

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