siRNA, Anti-CASTOR1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66419WQ-2OMe)

The product SIRGT66419WQ-2OMe is a type of small interfering RNA (siRNA) that targets CASTOR1 gene and regulates the expression of gene. The siRNA interferes with the expression of CASTOR1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001037666.2
Alternative Names GATSL3
Related Diseases mTOR signaling pathway (KEGG)
Purification HPLC
Target Gene
Gene ID 652968
Uniprot ID Q8WTX7
Sub Cat Target Species Modification Scale  
SIRGT67419WQ-2F CASTOR1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68419WQ-2MOE CASTOR1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69419WQ-LNA CASTOR1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66419WQ-RB CASTOR1 Human Ribo-modified Inquiry
SIRGT67419WQ-BB CASTOR1 Human Backbone-modified Inquiry

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