siRNA, Anti-CGNL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51159WQ-2OMe)

The product SIRGT51159WQ-2OMe is a type of small interfering RNA (siRNA) that targets CGNL1 gene and regulates the expression of gene. The siRNA interferes with the expression of CGNL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001252335.1
Alternative Names JACOP; PCING
Related Diseases Aromatase Excess Syndrome
Purification HPLC
Target Gene
Gene ID 84952
Uniprot ID Q0VF96
Sub Cat Target Species Modification Scale  
SIRGT52159WQ-2F CGNL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53159WQ-2MOE CGNL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54159WQ-LNA CGNL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51159WQ-RB CGNL1 Human Ribo-modified Inquiry
SIRGT52159WQ-BB CGNL1 Human Backbone-modified Inquiry

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