siRNA, Anti-CHRDL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51507WQ-2OMe)

The product SIRGT51507WQ-2OMe is a type of small interfering RNA (siRNA) that targets CHRDL1 gene and regulates the expression of gene. The siRNA interferes with the expression of CHRDL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001143981.1
Alternative Names CHL; MGC1; MGCN; NRLN1; VOPT; dA141H5.1
Related Diseases Megalocornea
Purification HPLC
Target Gene
Gene ID 91851
Uniprot ID Q9BU40
Sub Cat Target Species Modification Scale  
SIRGT52507WQ-2F CHRDL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53507WQ-2MOE CHRDL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54507WQ-LNA CHRDL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51507WQ-RB CHRDL1 Human Ribo-modified Inquiry
SIRGT52507WQ-BB CHRDL1 Human Backbone-modified Inquiry

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