siRNA, Anti-CLRN2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT69638WQ-LNA)

The product SIRGT69638WQ-LNA is a type of small interfering RNA (siRNA) that targets CLRN2 gene and regulates the expression of gene. The siRNA interferes with the expression of CLRN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001079827.2
Related Diseases Acute Hemorrhagic Leukoencephalitis
Purification HPLC
Target Gene
Gene ID 645104
Uniprot ID A0PK11
Sub Cat Target Species Modification Scale  
SIRGT66638WQ-2OMe CLRN2 Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT67638WQ-2F CLRN2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68638WQ-2MOE CLRN2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT66638WQ-RB CLRN2 Human Ribo-modified Inquiry
SIRGT67638WQ-BB CLRN2 Human Backbone-modified Inquiry

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