siRNA, Anti-COA4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76163WQ-2OMe)

The product SIRGT76163WQ-2OMe is a type of small interfering RNA (siRNA) that targets COA4 gene and regulates the expression of gene. The siRNA interferes with the expression of COA4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016565.2
Alternative Names CHCHD8; CMC3; E2IG2
Related Diseases Cardiomyopathy
Purification HPLC
Target Gene
Gene ID 51287
Uniprot ID Q9NYJ1
Sub Cat Target Species Modification Scale  
SIRGT77163WQ-2F COA4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78163WQ-2MOE COA4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79163WQ-LNA COA4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76163WQ-RB COA4 Human Ribo-modified Inquiry
SIRGT77163WQ-BB COA4 Human Backbone-modified Inquiry

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