siRNA, Anti-COL6A5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT61543WQ-2OMe)

The product SIRGT61543WQ-2OMe is a type of small interfering RNA (siRNA) that targets COL6A5 gene and regulates the expression of gene. The siRNA interferes with the expression of COL6A5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001278298.1
Alternative Names COL29A1; VWA4
Related Diseases Chronic Dacryoadenitis
Purification HPLC
Target Gene
Gene ID 256076
Uniprot ID A8TX70
Sub Cat Target Species Modification Scale  
SIRGT62543WQ-2F COL6A5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT63543WQ-2MOE COL6A5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT64543WQ-LNA COL6A5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT61543WQ-RB COL6A5 Human Ribo-modified Inquiry
SIRGT62543WQ-BB COL6A5 Human Backbone-modified Inquiry

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