siRNA, Anti-COLCA2, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT51845WQ-2OMe)

The product SIRGT51845WQ-2OMe is a type of small interfering RNA (siRNA) that targets COLCA2 gene and regulates the expression of gene. The siRNA interferes with the expression of COLCA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001136105.2
Alternative Names C11orf93; CASC13; LOH11CR1G
Related Diseases Colorectal Cancer
Purification HPLC
Target Gene
Gene ID 120376
Uniprot ID A8K830
Sub Cat Target Species Modification Scale  
SIRGT52845WQ-2F COLCA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53845WQ-2MOE COLCA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT51845WQ-RB COLCA2 Human Ribo-modified Inquiry
SIRGT52845WQ-BB COLCA2 Human Backbone-modified Inquiry

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