siRNA, Anti-COQ10A, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT53604WQ-2MOE)
The product SIRGT53604WQ-2MOE is a type of small interfering RNA (siRNA) that targets COQ10A gene and regulates the expression of gene. The siRNA interferes with the expression of COQ10A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001099337.1 |
| Related Diseases | Familial Hypercholesterolemia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT51604WQ-2OMe | COQ10A | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT52604WQ-2F | COQ10A | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT54604WQ-LNA | COQ10A | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT86911WQ-2OMe | Coq10a | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT87911WQ-2F | Coq10a | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT88911WQ-2MOE | Coq10a | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT89911WQ-LNA | Coq10a | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT51604WQ-RB | COQ10A | Human | Ribo-modified | ||
| SIRGT86911WQ-RB | Coq10a | Mouse | Ribo-modified | ||
| SIRGT52604WQ-BB | COQ10A | Human | Backbone-modified | ||
| SIRGT87911WQ-BB | Coq10a | Mouse | Backbone-modified |
