siRNA, Anti-COQ4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT78174WQ-2MOE)
The product SIRGT78174WQ-2MOE is a type of small interfering RNA (siRNA) that targets COQ4 gene and regulates the expression of gene. The siRNA interferes with the expression of COQ4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_016035.4 |
| Alternative Names | CGI-92; COQ10D7 |
| Related Diseases | Coenzyme Q10 Deficiency, Primary, 7 |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT76174WQ-2OMe | COQ4 | Human | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT77174WQ-2F | COQ4 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT79174WQ-LNA | COQ4 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT97067WQ-2F | Coq4 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT98067WQ-2MOE | Coq4 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT99067WQ-LNA | Coq4 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT76174WQ-RB | COQ4 | Human | Ribo-modified | ||
| SIRGT96067WQ-RB | Coq4 | Mouse | Ribo-modified | ||
| SIRGT77174WQ-BB | COQ4 | Human | Backbone-modified | ||
| SIRGT97067WQ-BB | Coq4 | Mouse | Backbone-modified |
