siRNA, Anti-CRIM1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76185WQ-2OMe)

The product SIRGT76185WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRIM1 gene and regulates the expression of gene. The siRNA interferes with the expression of CRIM1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016441.2
Alternative Names CRIM-1; S52
Related Diseases Macrophthalmia
Purification HPLC
Target Gene
Gene ID 51232
Uniprot ID Q9NZV1
Sub Cat Target Species Modification Scale  
SIRGT77185WQ-2F CRIM1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78185WQ-2MOE CRIM1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79185WQ-LNA CRIM1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76185WQ-RB CRIM1 Human Ribo-modified Inquiry
SIRGT77185WQ-BB CRIM1 Human Backbone-modified Inquiry

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