siRNA, Anti-CRNKL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76187WQ-2OMe)

The product SIRGT76187WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRNKL1 gene and regulates the expression of gene. The siRNA interferes with the expression of CRNKL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016652.5
Alternative Names CLF; CRN; Clf1; HCRN; MSTP021; SYF3
Related Diseases Fanconi Anemia
Purification HPLC
Target Gene
Gene ID 51340
Uniprot ID Q9BZJ0
Sub Cat Target Species Modification Scale  
SIRGT77187WQ-2F CRNKL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78187WQ-2MOE CRNKL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79187WQ-LNA CRNKL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76187WQ-RB CRNKL1 Human Ribo-modified Inquiry
SIRGT77187WQ-BB CRNKL1 Human Backbone-modified Inquiry

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