siRNA, Anti-CRYL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76189WQ-2OMe)

The product SIRGT76189WQ-2OMe is a type of small interfering RNA (siRNA) that targets CRYL1 gene and regulates the expression of gene. The siRNA interferes with the expression of CRYL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015974.2
Alternative Names GDH; HEL30; lambda-CRY
Related Diseases Autosomal Recessive 1B
Purification HPLC
Target Gene
Gene ID 51084
Uniprot ID Q9Y2S2
Sub Cat Target Species Modification Scale  
SIRGT77189WQ-2F CRYL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78189WQ-2MOE CRYL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79189WQ-LNA CRYL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76189WQ-RB CRYL1 Human Ribo-modified Inquiry
SIRGT77189WQ-BB CRYL1 Human Backbone-modified Inquiry

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