siRNA, Anti-DDX41, 2'-F/LNA/Ribo/Backbone-modified(CAT#: SIRGT77216WQ-2F)
The product SIRGT77216WQ-2F is a type of small interfering RNA (siRNA) that targets DDX41 gene and regulates the expression gene. The siRNA interferes with the expression DDX41 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_016222.3 |
| Alternative Names | ABS; MPLPF |
| Related Diseases | Myeloproliferative/Lymphoproliferative Neoplasms |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT79216WQ-LNA | DDX41 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT76216WQ-RB | DDX41 | Human | Ribo-modified | ||
| SIRGT77216WQ-BB | DDX41 | Human | Backbone-modified |
