siRNA, Anti-DEFB118, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66708WQ-2OMe)

The product SIRGT66708WQ-2OMe is a type of small interfering RNA (siRNA) that targets DEFB118 gene and regulates the expression of gene. The siRNA interferes with the expression of DEFB118 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_054112.2
Alternative Names C20orf63; DEFB-18; ESC42; ESP13.6
Related Diseases Vulvitis
Purification HPLC
Target Gene
Gene ID 117285
Uniprot ID Q96PH6
Sub Cat Target Species Modification Scale  
SIRGT67708WQ-2F DEFB118 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT68708WQ-2MOE DEFB118 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT69708WQ-LNA DEFB118 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT66708WQ-RB DEFB118 Human Ribo-modified Inquiry
SIRGT67708WQ-BB DEFB118 Human Backbone-modified Inquiry

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