siRNA, Anti-DEFB127, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT66430WQ-2OMe)
The product SIRGT66430WQ-2OMe is a type of small interfering RNA (siRNA) that targets DEFB127 gene and regulates the expression of gene. The siRNA interferes with the expression of DEFB127 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_139074.3 |
| Alternative Names | C20orf73; DEF-27; DEFB-27; DEFB27; bA530N10.2; hBD-27 |
| Related Diseases | Testicular Infarct |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT67430WQ-2F | DEFB127 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT68430WQ-2MOE | DEFB127 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT69430WQ-LNA | DEFB127 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT66430WQ-RB | DEFB127 | Human | Ribo-modified | ||
| SIRGT67430WQ-BB | DEFB127 | Human | Backbone-modified |
