siRNA, Anti-DEFB134, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT66284WQ-2OMe)

The product SIRGT66284WQ-2OMe is a type of small interfering RNA (siRNA) that targets DEFB134 gene and regulates the expression of gene. The siRNA interferes with the expression of DEFB134 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001302695.1
Related Diseases Diaphragmatic Hernia
Purification HPLC
Target Gene
Gene ID 613211
Uniprot ID Q4QY38
Sub Cat Target Species Modification Scale  
SIRGT67284WQ-2F DEFB134 Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT68284WQ-2MOE DEFB134 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT69284WQ-LNA DEFB134 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT67284WQ-RB DEFB134 Human Ribo-modified Inquiry

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