siRNA, Anti-DNAI1, 2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT73384WQ-2MOE)

The product SIRGT73384WQ-2MOE is a type of small interfering RNA (siRNA) that targets DNAI1 gene and regulates the expression of gene. The siRNA interferes with the expression of DNAI1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012144.3
Alternative Names CILD1; DIC1; ICS1; PCD
Related Diseases Ciliary Dyskinesia, Primary, 1
Purification HPLC
Target Gene
Gene ID 27019
Uniprot ID Q9UI46
Sub Cat Target Species Modification Scale  
SIRGT71384WQ-2OMe DNAI1 Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT74384WQ-LNA DNAI1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT72384WQ-BB DNAI1 Human Backbone-modified Inquiry

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