siRNA, Anti-EDARADD, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT56161WQ-2OMe)

The product SIRGT56161WQ-2OMe is a type of small interfering RNA (siRNA) that targets EDARADD gene and regulates the expression of gene. The siRNA interferes with the expression of EDARADD gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_080738.3
Alternative Names ECTD11A; ECTD11B; ED3; EDA3
Related Diseases Ectodermal Dysplasia 11B
Purification HPLC
Target Gene
Gene ID 128178
Uniprot ID Q8WWZ3
Sub Cat Target Species Modification Scale  
SIRGT86530WQ-2OMe Edaradd Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT87530WQ-2F Edaradd Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT89530WQ-LNA Edaradd Mouse Locked Nucleic Acid (LNA) Inquiry
SIRGT56161WQ-RB EDARADD Human Ribo-modified Inquiry
SIRGT86530WQ-RB Edaradd Mouse Ribo-modified Inquiry
SIRGT57161WQ-BB EDARADD Human Backbone-modified Inquiry
SIRGT87530WQ-BB Edaradd Mouse Backbone-modified Inquiry

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