siRNA, Anti-EHF, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT74278WQ-LNA)

The product SIRGT74278WQ-LNA is a type of small interfering RNA (siRNA) that targets EHF gene and regulates the expression of gene. The siRNA interferes with the expression of EHF gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012153.5
Alternative Names ESE3; ESE3B; ESEJ
Related Diseases Brachydactyly, Type A3
Purification HPLC
Target Gene
Gene ID 26298
Uniprot ID Q9NZC4
Sub Cat Target Species Modification Scale  
SIRGT71278WQ-2OMe EHF Human 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT72278WQ-2F EHF Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73278WQ-2MOE EHF Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT71278WQ-RB EHF Human Ribo-modified Inquiry
SIRGT72278WQ-BB EHF Human Backbone-modified Inquiry

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