siRNA, Anti-FBXL4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT71236WQ-2OMe)

The product SIRGT71236WQ-2OMe is a type of small interfering RNA (siRNA) that targets FBXL4 gene and regulates the expression of gene. The siRNA interferes with the expression of FBXL4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012160.4
Alternative Names FBL4; FBL5; MTDPS13
Related Diseases Mitochondrial Dna Depletion Syndrome 13
Purification HPLC
Target Gene
Gene ID 26235
Uniprot ID Q9UKA2
Sub Cat Target Species Modification Scale  
SIRGT72236WQ-2F FBXL4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT73236WQ-2MOE FBXL4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT74236WQ-LNA FBXL4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT71236WQ-RB FBXL4 Human Ribo-modified Inquiry
SIRGT72236WQ-BB FBXL4 Human Backbone-modified Inquiry

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