siRNA, Anti-GJA10, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT51025WQ-2OMe)

The product SIRGT51025WQ-2OMe is a type of small interfering RNA (siRNA) that targets GJA10 gene and regulates the expression of gene. The siRNA interferes with the expression of GJA10 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032602.1
Alternative Names CX62
Related Diseases Deafness, Autosomal Dominant 66
Purification HPLC
Target Gene
Gene ID 84694
Uniprot ID Q969M2
Sub Cat Target Species Modification Scale  
SIRGT52025WQ-2F GJA10 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53025WQ-2MOE GJA10 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT54025WQ-LNA GJA10 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT51025WQ-RB GJA10 Human Ribo-modified Inquiry
SIRGT52025WQ-BB GJA10 Human Backbone-modified Inquiry

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