siRNA, Anti-GNMT, 2'-F/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT77326WQ-2F)
The product SIRGT77326WQ-2F is a type of small interfering RNA (siRNA) that targets GNMT gene and regulates the expression gene. The siRNA interferes with the expression GNMT gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_018960.5 |
| Alternative Names | HEL-S-182mP |
| Related Diseases | Glycine N-Methyltransferase Deficiency |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT78326WQ-2MOE | GNMT | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT79326WQ-LNA | GNMT | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT76326WQ-RB | GNMT | Human | Ribo-modified |
