siRNA, Anti-GNPDA2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT56318WQ-2OMe)

The product SIRGT56318WQ-2OMe is a type of small interfering RNA (siRNA) that targets GNPDA2 gene and regulates the expression of gene. The siRNA interferes with the expression of GNPDA2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001270880.1
Alternative Names GNP2; SB52
Related Diseases Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1
Purification HPLC
Target Gene
Gene ID 132789
Uniprot ID Q8TDQ7
Sub Cat Target Species Modification Scale  
SIRGT57318WQ-2F GNPDA2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT58318WQ-2MOE GNPDA2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT59318WQ-LNA GNPDA2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT56318WQ-RB GNPDA2 Human Ribo-modified Inquiry
SIRGT57318WQ-BB GNPDA2 Human Backbone-modified Inquiry

Related Products