siRNA, Anti-HIGD2B, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT51936WQ-2OMe)

The product SIRGT51936WQ-2OMe is a type of small interfering RNA (siRNA) that targets HIGD2B gene and regulates the expression of gene. The siRNA interferes with the expression of HIGD2B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001350932.1
Alternative Names HIGD2BP
Related Diseases Bardet-Biedl Syndrome 4
Purification HPLC
Target Gene
Gene ID 123346
Uniprot ID Q4VC39
Sub Cat Target Species Modification Scale  
SIRGT52936WQ-2F HIGD2B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT53936WQ-2MOE HIGD2B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT51936WQ-RB HIGD2B Human Ribo-modified Inquiry
SIRGT52936WQ-BB HIGD2B Human Backbone-modified Inquiry

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