siRNA, Anti-HPGDS, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76367WQ-2OMe)

The product SIRGT76367WQ-2OMe is a type of small interfering RNA (siRNA) that targets HPGDS gene and regulates the expression of gene. The siRNA interferes with the expression of HPGDS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_014485.2
Alternative Names GSTS; GSTS1; GSTS1-1; PGD2; PGDS
Related Diseases Hypertrophic Osteoarthropathy
Purification HPLC
Target Gene
Gene ID 27306
Uniprot ID P15428
Sub Cat Target Species Modification Scale  
SIRGT77367WQ-2F HPGDS Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78367WQ-2MOE HPGDS Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79367WQ-LNA HPGDS Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76367WQ-RB HPGDS Human Ribo-modified Inquiry
SIRGT77367WQ-BB HPGDS Human Backbone-modified Inquiry

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