siRNA, Anti-INPP5J, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76396WQ-2OMe)

The product SIRGT76396WQ-2OMe is a type of small interfering RNA (siRNA) that targets INPP5J gene and regulates the expression of gene. The siRNA interferes with the expression of INPP5J gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001284289.1
Alternative Names INPP5; PIB5PA; PIPP
Related Diseases Lowe Oculocerebrorenal Syndrome
Purification HPLC
Target Gene
Gene ID 27124
Uniprot ID Q15735
Sub Cat Target Species Modification Scale  
SIRGT77396WQ-2F INPP5J Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78396WQ-2MOE INPP5J Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79396WQ-LNA INPP5J Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76396WQ-RB INPP5J Human Ribo-modified Inquiry
SIRGT77396WQ-BB INPP5J Human Backbone-modified Inquiry

Related Products