siRNA, Anti-INPP5K, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT76397WQ-2OMe)

The product SIRGT76397WQ-2OMe is a type of small interfering RNA (siRNA) that targets INPP5K gene and regulates the expression of gene. The siRNA interferes with the expression of INPP5K gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_130766.2
Alternative Names MDCCAID; PPS; SKIP
Related Diseases Marinesco-Sjogren Syndrome
Purification HPLC
Target Gene
Gene ID 51763
Uniprot ID Q9BT40
Sub Cat Target Species Modification Scale  
SIRGT77397WQ-2F INPP5K Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78397WQ-2MOE INPP5K Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79397WQ-LNA INPP5K Human Locked Nucleic Acid (LNA) Inquiry
SIRGT77397WQ-BB INPP5K Human Backbone-modified Inquiry

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